FUNCTIONAL MAGNETIC RESONANCE IMAGING HUETTEL PDF
PDF | On Apr 1, , Lubdha M Shah and others published Functional Magnetic observe brain function with MRI during speciﬁc tasks and Huettel SA, Song AW, McCarthy G: Signal, noise and preprocessing of. fMRI. HST Functional Magnetic Resonance Imaging: Data Acquisition and Huettel S, Song AW, McCarthy G. Funcitonal Magnetic Resonance Imaging, . Textbook on fMRI. (3rd edition) by. Huettel, Song &. McCarthy resourceone.info resourceone.info resourceone.info
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Scott A. Huettel, Allen W. Song, Gregory McCarthy. Functional Magnetic Resonance Imaging. 2nd edition. Sinauer Associates Inc.: Sunderland, MA . FUNCTIONAL. Magnetic Resonance Imaging. SECOND EDITION. Scott A. Huettel. Brain Imaging and Analysis Center, Duke University. Allen W. Song. Functional Magnetic Resonance Imaging Huettel - Ebook download as PDF File .pdf) or read book online.
Society for Social Neuroscience
Many of the most tantalizing ideas await empirical support and have not yet crystallized into guiding theory. Therefore, we introduce key concepts ill a logical, straightforward manner, with clear definitions of research jargon.
Throughout the book, we illustrate ideas by describing the primary research studies that support or disconfirm them. We present abstract ideas ill the context of real-world fMRI studies, so that students can make informed deci sions about research questions.
Finally, we present ideas in a format that can be easily understood by beglnnilg l researchers, whether undergraduate students, graduate students, postdoctoral fellows, or research faculty. We recognize that many aspects of fMRI seem very technical to those new to the field. Yet these concepts are important and cannot be omitted simply to reduce the complexity of the book.
The textbook contains 14 chapters, each covering a discrete aspect of fMRI, with a clear progression across topics. Throughout the book, a large number of exciting concepts are set aside ill boxes for special emphasis. These boxes make ideal stepping-off points for instructors to delve more deeply into the literature.
More than figures are included, many new to this edition. In addition to the standard glossary at the end of the book, key terms are defined ill the margins at their first occurrence ill a chapter.
Each chapter includes several thought problems to challenge the reader's understanding. Two types of references are included: Suggested Readings and Chapter References.
Functional Magnetic Resonance Imaging, Second Edition
A statistical program then calculates what combination of regression weights best predicts the experimental data. Data from different subjects is combined using fixed- or random-effects approaches; for most experiments, random-effects approaches are preferable because they allow extension of the results to the population from which the subject sample is drawn.
After statistical values are determined for each brain voxel, typically using the regression approaches described above, researchers must determine which of those voxels exhibit real experimental effects. Because a typical fMRI data set contains tens of thousands of voxels, conventional statistical testing e.
Yet, using very strict correction factors e. For fMRI data, the true number of independent comparisons can be orders of magnitude smaller than the number of voxels. Another, nonexclusive approach is to require clusters of activation to reach a particular size e.
The final outputs of fMRI analyses are maps indicating which brain voxels exhibited BOLD signal changes consistent with the cognitive processes manipulated in the experiment.
Displaying and Interpreting fMRI Data A striking image of a high-resolution brain with colored patches Figure 6 can suggest a photograph of the brain in action.
The apparent detail of the background MRI images — or three-dimensional renderings — seemingly implies exquisite spatial resolution. And, a colored area of activation can be interpreted as the single module that supports some particular process, whether perceiving faces, making decisions, or evaluating numbers.
All of these intuitions are false. The images arising from fMRI experiments are not photographs; they reflect the statistical confidence that a particular brain region expresses a particular function.
Bright colors usually indicate regions where there is strong evidence that the experimental manipulation affected the BOLD signal, while uncolored regions lacked any significant statistical effect. The resolution of fMRI maps is relatively coarse, both because the images are usually acquired at 3—5 mm Figure 6 fMRI data displayed on a high-resolution rendered brain. Shown are maps of fMRI activation derived from a visual perception task, here displayed on a high-resolution brain that has been rendered into a three-dimensional surface.
Part of the parietal lobe has been cut away to show deeper brain structures. And, the identification of a single active region does not rule out the possibilities that many other regions may contribute — or that the experiment may not have sufficient power to identify other effects.
Future Directions fMRI has become a dominant — and ubiquitous — research method in human cognitive neuroscience.
The collection of fMRI data has become so pervasive that new MRI scanners, even those for clinical use, come equipped with hardware, pulse sequences, and online analysis programs for fMRI experiments.
Given this maturity, from where will the next advances in fMRI arise? One possibility is increased field strength. In the early years of fMRI, there was a continual push toward high-field i.
Functional Magnetic Resonance Imaging
Now, 3 T and higher-field machines are common, both in research and clinical settings, and further improvements in field strength seem likely to be Functional MRI fMRI incremental at best. Another possibility is improved spatial and temporal resolution.
While some new techniques have arisen e. The book progresses logically from MR scanners and signals to the connection between neuronal and hemodynamic activity to experimental design and statistical analyses while walking the reader through the relevant aspects of physiology and physics along the way.
While Functional Magnetic Resonance Imaging does not qualify its reader as capable of designing and executing groundbreaking experimentation with fMRI, it was not written for that purpose. In fact, it achieves its intended goal very effectively: It lays the requisite groundwork for further study and gives the student a baseline familiarity with all of the terms and subjects likely to be necessary for a deeper understanding of fMRI.
This text allows the reader to take their first step into the rapidly expanding field of cognitive neuroscience research enabled by fMRI and does so in a painless and all-inclusive fashion.
National Center for Biotechnology Information , U. Yale J Biol Med. Reviewed by Matthew J.
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Matthew J.We begin the textbook by establishing strong foundations in the physics and biology of fMRI. Matthew J. Drug studies are powerful, in that they allow the investigation of large-scale brain systems that are not associated with simple lesions, and they are clinically relevant, in that many drugs have well-understood effects on brain disorders e.
National Center for Biotechnology Information , U. Measuring Brain Function Single-unit recording Box Thus, we also refer to these images as T1-contrast images. Because the various techniques measure different aspects of brain function, they differ in their strengths and weaknesses.